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The main targets of the predicted drugs and our list of predicted essential genes had a higher median dependency probability (likelihood that the knock-out of a gene reduces cell growth or induces cell death) than targets of known anti-melanoma drugs (Fig

Methods: A systematic scoping review following PRISMA-ScR guidelines searched PubMed, MEDLINE, CINAHL, CENTRAL, and IEEE Xplore for quantitative studies (2014-2024)